IL-33 Expression Is Lower in Current Smokers at Both Transcriptomic and Protein Level

- Faiz, Alen, Mahbub, Rashad M., Heijink, Irene H., Massip, Florian, de Biase, Maria Stella, Schwarz, Roland F., Adcock, Ian M., Chung, Kian F., van der Does, Anne, Hiemstra, Pieter S., Goulaouic, Helene, Xing, Heming, Boedijono, Fia Sabrina, Wark, Peter A., .,, Tomassen, Milan I., Kooistra, Wierd, Timens, Wim, Nawijn, Martijn, Hansbro, Philip M., Johansen, Matt D., Pouwels, Simon D.

Adverse roles of mast cell chymase-1 in chronic obstructive pulmonary disease

- Liu, Gang, Jarnicki, Andrew G., Paudel, Keshav R., Lu, Wenying, Wadhwa, Ridhima, Philp, Ashleigh M., Van Eeckhoutte, Hannelore, Marshall, Jacqueline E., Malyla, Vamshikrishna, Katsifis, Angelica, Fricker, Michael, Hansbro, Nicole G., Dua, Kamal, Kermani, Nazanin Z., Eapen, Mathew S., Tiotiu, Angelica, Chung, K. Fan, Caramori, Gaetano, Bracke, Ken, Adcock, Ian M., Wark, Peter A., Hansbro, Philip M.

Adverse roles of mast cell chymase-1 in COPD

- Liu, Gang, Jarnicki, Andrew G., Fricker, Michael, Hansbro, Nicole G., Dua, Kamal, Kermani, Nazanin Z., Eapen, Mathew S., Tiotiu, Angelica, Chung, K. Fan, Caramori, Gaetano, Bracke, Ken, Adcock, Ian M., Paudel, Keshav R., Sohal, Sukhwinder S., Wark, Peter A., Oliver, Brian G., Hansbro, Philip M., Lu, Wenying, Wadhwa, Ridhima, Philp, Ashleigh M., Van Eeckhoutte, Hannelore, Marshall, Jacqueline E., Malyla, Vamshikrishna, Katsifis, Angelica

Pathways linked to unresolved inflammation and airway remodelling characterize the transcriptome in two independent severe asthma cohorts

- Sánchez-Ovando, Stephany, Pavlidis, Stelios, Wark, Peter A. B., Kermani, Nazanin Zounemat, Baines, Katherine Joanne, Barker, Daniel, Gibson, Peter G., Wood, Lisa G., Adcock, Ian M., Chung, Kian Fan, Simpson, Jodie Louise

Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma

- Pinkerton, James W., Kim, Richard Y., Baines, Katherine J., Starkey, Malcolm R., Kermani, Nazanin Z., Guo, Yi-Ke, Robertson, Avril A. B., O'Neill, Luke A. J., Adcock, Ian M., Cooper, Matthew A., Gibson, Peter G., Wood, Lisa G., Brown, Alexandra C., Hansbro, Philip M., Horvat, Jay C., Rae, Brittany E., Donovan, Chantal, Mayall, Jemma R., Carroll, Olivia R., Ali, Md. Khadem, Scott, Hayley A., Berthon, Bronwyn S.

Sputum macrophage diversity and activation in asthma: Role of severity and inflammatory phenotype

- Tiotiu, Angelica, Zounemat Kermani, Nazanin, Badi, Yusef, Pavlidis, Stelios, Hansbro, Philip M., Guo, Yi-Ke, Chung, Kian Fan, Adcock, Ian M.

Host-microbe cross-talk in the lung microenvironment: implications for understanding and treating chronic lung disease

- Gosens, Reinoud, Hiemstra, Pieter S., Adcock, Ian M., Bracke, Ken R., Dickson, Robert P., Hansbro, Philip M., Krauss-Etschmann, Ssusanne, Smits, Hermelijn H., Stassen, Frank R. M., Bartel, Sabine

Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline

- Holguin, Fernando, Cardet, Juan Carlos, Chung, Kian Fan, Diver, Sarah, Ferreira, Diogenes S., Fitzpatrick, Anne, Gaga, Mina, Kellermeyer, Liz, Khurana, Sandhya, Knight, Shandra, McDonald, Vanessa M., Morgan, Rebecca L., Ortega, Victor E., Rigau, David, Subbarao, Padmaja, Tonia, Thomy, Adcock, Ian M., Bleecker, Eugene R., Brightling, Chris, Boulet, Louis-Philippe, Cabana, Michael, Gibson, Peter

New drugs under development for COPD

- Lo Bello, Federica, Hansbro, Philip M., Donovan, Chantal, Coppolino, Irene, Mumby, Sharon, Adcock, Ian M., Caramori, Gaetano

Cellular mechanisms underlying steroid-resistant asthma

- Wadhwa, Ridhima, Dua, Kamal, Adcock, Ian M., Horvat, Jay C., Kim, Richard Y., Hansbro, Philip M.

CSF3R/CD114 mediates infection-dependent transition to severe asthma

- Wang, Hao, FitzPatrick, Meaghan, Adcock, Ian M., Chung, Kian Fan, Anderson, Gary P., Vlahos, Ross, Wark, Peter, Bozinovski, Steven, Wilson, Nicholas J., Anthony, Desiree, Reading, Patrick C., Satzke, Catherine, Dunne, Eileen M., Licciardi, Paul V., Seow, Huei Jiunn, Nichol, Kristy

Functional effects of the microbiota in chronic respiratory disease

- Budden, Kurtis F., Shukla, Shakti D., Hansbro, Philip M., Rehman, Saima Firdous, Bowerman, Kate L., Keely, Simon, Hugenholtz, Philip, Armstrong-James, Darius P. H., Adcock, Ian M., Chotirmall, Sanjay H., Chung, Kian Fan

IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis

- Starkey, Malcolm R., Plank, Maximilian W., Donovan, Chantal, Hansbro, Nicole G., Nguyen, Duc H., Nair, Prema Mono, Kim, Richard Y., Horvat, Jay C., Kaiko, Gerard E., Durum, Scott K., Wark, Peter A., Sin, Don D., Casolari, Paolo, Caramori, Gaetano, Adcock, Ian M., Foster, Paul S., Hansbro, Philip M., Papi, Alberto, Pavlidis, Stelios, Guo, Yike, Cameron, Guy J. M., Haw, Tatt Jhong, Tam, Anthony, Obiedat, Maen

Mitochondrial ROS and NLRP3 inflammasome in acute ozone-induced murine model of airway inflammation and bronchial hyperresponsiveness

- Xu, Mengmeng, Wang, Lei, Chung, Kian Fan, Li, Feng, Wang, Muyun, Wang, Hanying, Zhang, Hai, Chen, Yuqing, Wang, Xiaohui, Gong, Jicheng, Zhang, Junfeng, Adcock, Ian M.

Molecular links between COPD and lung cancer: new targets for drug discovery?

- Caramori, Gaetano, Ruggeri, Paolo, Tuccari, Giovanni, Hansbro, Philip M., Adcock, Ian M., Mumby, Sharon, Ieni, Antonio, Lo Bello, Federica, Chaminka, Vrushali, Donovan, Chantal, Andò, Filippo, Nucera, Francesco, Coppolino, Irene

Toll-like receptor 2 and 4 have opposing roles in the pathogenesis of cigarette smoke-induced chronic obstructive pulmonary disease

- Haw, Tatt Jhong, Starkey, Malcolm R., Horvat, Jay C., Adcock, Ian M., Hansbro, Philip M., Pavlidis, Stelios, Fricker, Michael, Arthurs, Anya L., Nair, Prema M., Liu, Gang, Hanish, Irwan, Kim, Richard Y., Foster, Paul S.

Animal models of COPD: what do they tell us?

- Jones, Bernadette, Donovan, Chantal, Hansbro, Philip M., Liu, Gang, Gomez, Henry M., Chimankar, Vrushali, Harrison, Celese L., Wiegman, Cornelis H., Adcock, Ian M., Knight, Darryl A., Hirota, Jeremy A.

Is mitochondrial dysfunction a driving mechanism linking COPD to nonsmall cell lung carcinoma?

- Ng Kee Kwong, Francois, Nicholson, Andrew G., Harrison, Celeste L., Hansbro, Philip M., Adcock, Ian M., Chung, Kian Fan

MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase-mediated suppression of histone deacetylase 2

- Kim, Richard Y., Horvat, Jay C., Sunkara, Krishna P., Nguyen, Thi Hiep, Jarnicki, Andrew G., Keely, Simon, Mattes, Joerg, Adcock, Ian M., Foster, Paul S., Hansbro, Philip M., Pinkerton, James W., Starkey, Malcolm R., Essilfie, Ama T., Mayall, Jemma R., Nair, Prema M., Hansbro, Nicole G., Jones, Bernadette, Haw, Tatt Jhong

The MIF antagonist ISO-1 attenuates corticosteroid-insensitive inflammation and airways hyperresponsiveness in an ozone-induced model of COPD

- Russell, Kirsty E., Chung, Kian Fan, Starkey, Malcolm R., Hansbro, Philip M., Adcock, Ian M., Wiegman, Coen H., Clarke, Colin J., Durham, Andrew L., Mallia, Patrick, Footit, Joseph, Johnston, Sebastian L., Barnes, Peter J., Hall, Simon R., Simpson, Karen D.